Olsalazine Disodium (Standard)
Olsalazine Disodium (Standard) is an orally active prodrug of 5-ASA (HY-15027). Olsalazine Disodium (Standard) can inhibit cells proliferation and induce apoptosis. Olsalazine Disodium (Standard) can reduce DAI and MPO activity and inhibit inflammatory cytokines levels. Olsalazine Disodium (Standard) can be used for the researches of cancer, inflammation and metabolic disease, such as colorectal cancer, inflammatory bowel disease (IBD) and hyperuricemic.
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- Pureté: 98%
- CAS No.: 6054-98-4
- Formule: C14H8N2Na2O6
- Masse moléculaire:346.20
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 6054-98-4
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Masse moléculaire 346.20
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Formule C14H8N2Na2O6
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SMILES
O=C(O[Na])C1=C(O)C=CC(/N=N/C2=CC(C(O[Na])=O)=C(O)C=C2)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Brown WA, et al. 5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer. Dig Dis Sci. 2000 Aug;45(8):1578-84. [Content Brief]
[2]. Thapa D, et al. Cannabidiol Enhances the Therapeutic Efficacy of Olsalazine and Cyclosporine in a Murine Model of Colitis. Int J Mol Sci. 2025 Aug 16;26(16):7913. [Content Brief]
[3]. Niu Y, et al. Olsalazine Sodium Increases Renal Urate Excretion by Modulating Urate Transporters in Hyperuricemic Animals. Biol Pharm Bull. 2020 Nov 1;43(11):1653-1659. [Content Brief]
[4]. Itoh S, et al. Olsalazine inhibits cell proliferation and DNA methylation in canine lymphoid tumor cell lines. Pol J Vet Sci. 2021 Dec;24(4):515-523. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)