Orexin receptor antagonist 4
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist with an IC50 of 4.27 nM. Orexin receptor antagonist 4 is 61-fold selective for the OX2R over the OX1R (IC50 of 295 nM) (WO2018206959A1; example 1).
For research use only. We do not sell to patients.
- CAS No.: 2251017-69-1
- Formula: C23H25FN4O2
- Molecular Weight:408.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Orexin Receptor (OX Receptor) Isoforms
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Biological Activity
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OX2 Receptor 4.27 nM (IC50) |
OX1 Receptor 295 nM (IC50) |
Chemical Information
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CAS No. 2251017-69-1
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Molecular Weight 408.47
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Formula C23H25FN4O2
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SMILES
[H][C@@]12CN(C[C@@]1(CN([C@H]2C)C(C3=CC=C(C=C3F)OC)=O)[H])C4=NC(C)=C(C(C)=C4)C#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Orexin receptor antagonist 4 Related Classifications
HY-146517 Related Classifications
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