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Cat. No.: HY-33037R

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Phenazine-1-carboxylic acid (Standard)

Name: Phenazine-1-carboxylic acid (Standard)
Brand: MedChemExpress
SKU: HY-33037R
Price: 44.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Phenazine-1-carboxylic acid (Standard) is the analytical standard of Phenazine-1-carboxylic acid. This product is intended for research and analytical applications. Phenazine-1-carboxylic acid is an antifungal agent. Additionally, Phenazine-1-carboxylic acid exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. Phenazine-1-carboxylic acid can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, demonstrating its potential immunomodulatory effects. Phenazine-1-carboxylic acid holds significant research value in the areas of anti-infection, anticancer, and immune response modulation[1][2][3][4].

For research use only. We do not sell to patients.

Purity: 99.63%
CAS No.: 2538-68-3
Formula: C₁₃H₈N₂O₂
Molecular Weight:224.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phenazine-1-carboxylic acid (Standard) Chemical Structure

CAS No.: 2538-68-3

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2538-68-3
Appearance Solid
Molecular Weight 224.22
Formula C₁₃H₈N₂O₂
Color Light green to green
SMILES

O=C(O)C1=C(N=C(C=CC=C2)C2=N3)C3=CC=C1
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
- Marine natural products
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cimmino A, et al. Phenazine-1-Carboxylic Acid (PCA), Produced for the First Time as an Antifungal Metabolite by Truncatella angustata, a Causal Agent of Grapevine Trunk Diseases (GTDs) in Iran. J Agric Food Chem. 2021 Oct 20;69(41):12143-12147. [Content Brief]

[2]. Karuppiah V, et al. Phenazine-1-carboxylic acid-induced programmed cell death in human prostate cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway[J]. journal of applied biomedicine, 2016, 14(3): 199-209.

[3]. Denning GM, et al. Phenazine-1-carboxylic acid, a secondary metabolite of Pseudomonas aeruginosa, alters expression of immunomodulatory proteins by human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2003 Sep;285(3):L584-92. [Content Brief]

[4]. Zhang L, et al. Antagonistic activity and mode of action of phenazine-1-carboxylic acid, produced by marine bacterium Pseudomonas aeruginosa PA31x, against Vibrio anguillarum in vitro and in a zebrafish in vivo model[J]. Frontiers in microbiology, 2017, 8: 289. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Phenazine-1-carboxylic acid (Standard)

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Phenazine-1-carboxylic acid (Standard)