Norstictic acid
Based on 1 Customer Validation
Norstictic acid is a potent and selective allossteric transcriptional regulator. Norstictic acid shows anticancer activity. Norstictic acid shows antioxidant activity and antimicrobial activity.
For research use only. We do not sell to patients.
- Purity: 96.6%
- CAS No.: 571-67-5
- Formula: C18H12O9
- Molecular Weight:372.28
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Norstictic acid significantly suppresses the TNBC MDA-MB-231 cell proliferation, migration, invasion with low toxicity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 571-67-5
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Appearance Solid
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Molecular Weight 372.28
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Formula C18H12O9
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Color White to off-white
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SMILES
O=CC1=C(OC(C(OC2=O)=C(C)C(O)=C34)=C3C(O)OC4=O)C2=C(C)C=C1O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Garlick JM, et al. Norstictic Acid Is a Selective Allosteric Transcriptional Regulator. J Am Chem Soc. 2021 Jun 30;143(25):9297-9302. [Content Brief]
[2]. Ebrahim HY, et al. Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C-Met. Phytother Res. 2016 Apr;30(4):557-66. [Content Brief]
[3]. Ranković B, et al. Biological activities of Toninia candida and Usnea barbata together with their norstictic acid and usnic acid constituents. Int J Mol Sci. 2012 Nov 12;13(11):14707-22. [Content Brief]
[4]. Tay T, et al. Evaluation of the antimicrobial activity of the acetone extract of the lichen Ramalina farinacea and its (+)-usnic acid, norstictic acid, and protocetraric acid constituents. Z Naturforsch C J Biosci. 2004 May-Jun;59(5-6):384-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)