Potassium succinate trihydrate
Based on 1 Customer Validation
Potassium succinate trihydrate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 6100-18-1
- Formula: C4H10K2O7
- Molecular Weight:248.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E805 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6100-18-1
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Appearance Solid
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Molecular Weight 248.31
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Formula C4H10K2O7
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Color White to off-white
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SMILES
O=C(CCC(O[K])=O)O[K].O.O.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 200 mg/mL (805.44 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.0272 mL | 20.1361 mL | 40.2722 mL | 100.6806 mL |
| 5 mM | 0.8054 mL | 4.0272 mL | 8.0544 mL | 20.1361 mL | |
| 10 mM | 0.4027 mL | 2.0136 mL | 4.0272 mL | 10.0681 mL | |
| 15 mM | 0.2685 mL | 1.3424 mL | 2.6848 mL | 6.7120 mL | |
| 20 mM | 0.2014 mL | 1.0068 mL | 2.0136 mL | 5.0340 mL | |
| 25 mM | 0.1611 mL | 0.8054 mL | 1.6109 mL | 4.0272 mL | |
| 30 mM | 0.1342 mL | 0.6712 mL | 1.3424 mL | 3.3560 mL | |
| 40 mM | 0.1007 mL | 0.5034 mL | 1.0068 mL | 2.5170 mL | |
| 50 mM | 0.0805 mL | 0.4027 mL | 0.8054 mL | 2.0136 mL | |
| 60 mM | 0.0671 mL | 0.3356 mL | 0.6712 mL | 1.6780 mL | |
| 80 mM | 0.0503 mL | 0.2517 mL | 0.5034 mL | 1.2585 mL | |
| 100 mM | 0.0403 mL | 0.2014 mL | 0.4027 mL | 1.0068 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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