1. Apoptosis
  2. Apoptosis
  3. POVPC

POVPC is an oxidized phospholipid can be found in in oxidatively modified low density lipoprotein (oxLDL). POVPC inhibits VSMC growth in high serum condition. POVPC induces apoptosis in low serum condition.

For research use only. We do not sell to patients.

POVPC Chemical Structure

POVPC Chemical Structure

CAS No. : 121324-31-0

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Description

POVPC is an oxidized phospholipid can be found in in oxidatively modified low density lipoprotein (oxLDL). POVPC inhibits VSMC growth in high serum condition. POVPC induces apoptosis in low serum condition[1].

In Vitro

POVPC (0-100 µM; 13 h) inhibits VSMC growth in a dose-dependent manner[1].
POVPC (50 µM; 2, 4, 6 h) induces apoptosis in a time-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: vascular smooth muscle cells (VSMC)
Concentration: 0-100 µM (under high serum conditions (10% FCS))
Incubation Time: 13 h
Result: Inhibited VSMC growth in a dose-dependent manner.

Apoptosis Analysis[1]

Cell Line: 7r5 cells
Concentration: 50 µM (0.1% FCS)
Incubation Time: 2, 4, 6 h
Result: Induced apoptosis in a time-dependent manner.
Molecular Weight

593.73

Formula

C29H56NO9P

CAS No.
SMILES

C[N+](C)(C)CCOP(OC[C@H](OC(CCCC=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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POVPC Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
POVPC
Cat. No.:
HY-130576
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