Presenilin 1 (349-361)
Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the research of various diseases.
For research use only. We do not sell to patients.
- CAS No.: 956004-39-0
- Formula: C56H93N21O19
- Molecular Weight:1364.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Presenilin 1 (349-361) reduces the interaction with beta-catenin leading to decreased phosphorylation and ubiquitination of beta-catenin when structural change, thereby increases its nuclear signaling and the transcription of target genes, including c-MYC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 956004-39-0
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Molecular Weight 1364.47
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Formula C56H93N21O19
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Sequence Shortening
GPHRSTPESRAAV
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)