Propane-1,3-diyl bis4-methylbenzenesulfonate
Based on 1 Customer Validation
Propane-1,3-diyl bis(4-methylbenzenesulfonate) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 5469-66-9
- Formula: C17H20O6S2
- Molecular Weight:384.46
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E807 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5469-66-9
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Appearance Solid
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Molecular Weight 384.46
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Formula C17H20O6S2
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Color White to off-white
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SMILES
O=S(=O)(OCCCOS(=O)(=O)C1=CC=C(C=C1)C)C2=CC=C(C=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (260.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6011 mL | 13.0053 mL | 26.0105 mL | 65.0263 mL |
| 5 mM | 0.5202 mL | 2.6011 mL | 5.2021 mL | 13.0053 mL | |
| 10 mM | 0.2601 mL | 1.3005 mL | 2.6011 mL | 6.5026 mL | |
| 15 mM | 0.1734 mL | 0.8670 mL | 1.7340 mL | 4.3351 mL | |
| 20 mM | 0.1301 mL | 0.6503 mL | 1.3005 mL | 3.2513 mL | |
| 25 mM | 0.1040 mL | 0.5202 mL | 1.0404 mL | 2.6011 mL | |
| 30 mM | 0.0867 mL | 0.4335 mL | 0.8670 mL | 2.1675 mL | |
| 40 mM | 0.0650 mL | 0.3251 mL | 0.6503 mL | 1.6257 mL | |
| 50 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3005 mL | |
| 60 mM | 0.0434 mL | 0.2168 mL | 0.4335 mL | 1.0838 mL | |
| 80 mM | 0.0325 mL | 0.1626 mL | 0.3251 mL | 0.8128 mL | |
| 100 mM | 0.0260 mL | 0.1301 mL | 0.2601 mL | 0.6503 mL |
Propane-1,3-diyl bis4-methylbenzenesulfonate Related Classifications
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