Prostaglandin F2α serinol amide
Based on 1 Customer Validation
Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord.
For research use only. We do not sell to patients.
- Purity : 99.41%
- CAS No.: 1135226-99-1
- Formula: C23H41NO6
- Molecular Weight:427.57
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Chemical Information
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CAS No. 1135226-99-1
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Appearance Oil
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Molecular Weight 427.57
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Formula C23H41NO6
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Color Colorless to light yellow
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SMILES
OCC(CO)NC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (233.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Richie-Jannetta R, et al. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):19-24. [Content Brief]
[2]. Woodward DF, et al. Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics. Pharmacol Rev. 2013 Jul 26;65(4):1135-47. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3388 mL | 11.6940 mL | 23.3880 mL | 58.4700 mL |
| 5 mM | 0.4678 mL | 2.3388 mL | 4.6776 mL | 11.6940 mL | |
| 10 mM | 0.2339 mL | 1.1694 mL | 2.3388 mL | 5.8470 mL | |
| 15 mM | 0.1559 mL | 0.7796 mL | 1.5592 mL | 3.8980 mL | |
| 20 mM | 0.1169 mL | 0.5847 mL | 1.1694 mL | 2.9235 mL | |
| 25 mM | 0.0936 mL | 0.4678 mL | 0.9355 mL | 2.3388 mL | |
| 30 mM | 0.0780 mL | 0.3898 mL | 0.7796 mL | 1.9490 mL | |
| 40 mM | 0.0585 mL | 0.2923 mL | 0.5847 mL | 1.4617 mL | |
| 50 mM | 0.0468 mL | 0.2339 mL | 0.4678 mL | 1.1694 mL | |
| 60 mM | 0.0390 mL | 0.1949 mL | 0.3898 mL | 0.9745 mL | |
| 80 mM | 0.0292 mL | 0.1462 mL | 0.2923 mL | 0.7309 mL | |
| 100 mM | 0.0234 mL | 0.1169 mL | 0.2339 mL | 0.5847 mL |