Protocatechuate 3,4-dioxygenase
Based on 1 publication(s) in Google Scholar
Protocatechuate 3,4-dioxygenase is a dioxygenase. Protocatechuate 3,4-dioxygenase belongs to the non-heme iron dioxygenase class. Protocatechuate 3,4-dioxygenase catalyzes the cleavage of the aromatic ring of 3,4-dihydroxybenzoate, attaching two atoms of molecular oxygen to the compound to generate β-carboxy-cis,cis-muconate. Protocatechuate 3,4-dioxygenase is a key enzyme in the β-ketoadipic acid pathway. It is found in marine bacteria associated with Roseobacter. Protocatechuate 3,4-dioxygenase can be isolated from Pseudomonas aeruginosa.
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- CAS No.: 9029-47-4
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Protocatechuate 3,4-dioxygenase
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Biological Activity
Protocatechuate 3,4-dioxygenase catalyzes the aromatic ring cleavage of 3,4-dihydroxybenzoate by incorporating both atoms of molecular oxygen to yield β-carboxy-cis,cis-muconate. Protocatechuate 3,4-dioxygenase is a key enzyme in the β-ketoadipate pathway. Protocatechuate 3,4-dioxygenase is present in marine bacteria affiliated with the Roseobacter group. Protocatechuate 3,4-dioxygenase can be isolated from Pseudomonas aeruginosa[1][2][3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1.13.11.3
≥3 U/mg soild
One unit is defined as the amount of enzyme that will causes the oxidation of 1 μmol of protocatechuate per minute at pH 7.5 and 37°C.
Chemical Information
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CAS No. 9029-47-4
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Appearance Solid
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Color Off-white to pale purple
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SMILES
[Protocatechuate 3,4-dioxygenase]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
2026 Feb 13:2026.02.12.705659. PMID: 41727155
Purity & Documentation
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Ohlendorf DH, et al. Structure and assembly of protocatechuate 3,4-dioxygenase. Nature. 1988 Nov 24;336(6197):403-5. [Content Brief]
[2]. Buchan A, et al. Key aromatic-ring-cleaving enzyme, protocatechuate 3,4-dioxygenase, in the ecologically important marine Roseobacter lineage. Appl Environ Microbiol. 2000 Nov;66(11):4662-72. [Content Brief]
[3]. Ohlendorf DH, et al. Structure of protocatechuate 3,4-dioxygenase from Pseudomonas aeruginosa at 2.15 A resolution. J Mol Biol. 1994 Dec 16;244(5):586-608. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocatechuate 3,4-dioxygenase Related Classifications
HY-P2915 Related Classifications
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