Pyrrolidine ricinoleamide
Pyrrolidine ricinoleamide ((R)-5d) is a fatty acid amide that exhibits effective antiproliferative activity against a series of cancer cells, including human glioma U251 cells. Pyrrolidine ricinoleamide can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1246776-23-7
- Formula: C22H41NO2
- Molecular Weight:351.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | GI50 |
4.1 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| MCF7 | GI50 |
4.4 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| NCI/ADR-RES | GI50 |
4 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| NCI-H460 | GI50 |
6.9 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| OVCAR-3 | GI50 |
4.3 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| PC-3 | GI50 |
6.2 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| U-251 | GI50 |
1.5 μg/mL
Compound: (R)-5d
|
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
Chemical Information
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CAS No. 1246776-23-7
-
Molecular Weight 351.57
-
Formula C22H41NO2
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SMILES
CCCCCC[C@@H](O)C/C=C\CCCCCCCC(N1CCCC1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)