(S)-α-Methylbenzyl ricinoleamide
(S)-α-Methylbenzyl ricinoleamide (compound (R,S)-3d) is a fatty acid amide. (S)-α-Methylbenzyl ricinoleamide shows antiproliferative activity, inhibits the growth of human ovarian cancer cells NCI-ADR/RES and glioma cells U251 with GI50s of 1.9 μg/mL and 3.6 μg/mL, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1246776-22-6
- Formula: C26H43NO2
- Molecular Weight:401.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | GI50 |
6.7 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| MCF7 | GI50 |
5.1 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| NCI/ADR-RES | GI50 |
1.9 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| NCI-H460 | GI50 |
8.3 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| OVCAR-3 | GI50 |
11.1 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| PC-3 | GI50 |
11.7 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
| U-251 | GI50 |
3.6 μg/mL
Compound: (R,S)-3d
|
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
|
[PMID: 25510639] |
Chemical Information
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CAS No. 1246776-22-6
-
Molecular Weight 401.63
-
Formula C26H43NO2
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SMILES
CCCCCC[C@@H](O)C/C=C\CCCCCCCC(N[C@H](C1=CC=CC=C1)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)