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(R)-Citramalate synthase

(R)-Citramalate synthase (EC 2.3.1.182) is involved in a novel pyruvate pathway for isoleucine biosynthesis that is found in some, mainly archaeal, bacteria. (R)-Citramalate synthase (EC 2.3.1.182) can be inhibited by isoleucine, the end-product of the pathway, but not by leucine. (R)-Citramalate synthase (EC 2.3.1.182) is highly specific for pyruvate as substrate.

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  • (R)-Citramalate synthase Chemical Structure
    (R)-Citramalate synthase Chemical Structure
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  • (R)-Citramalate synthase Chemical Structure
    (R)-Citramalate synthase Chemical Structure
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  • (R)-Citramalate synthase