(R)-(-)-N-Boc-3-pyrrolidinol-d4
(R)-(-)-N-Boc-3-pyrrolidinol-d4 is the d4-labeled (R)-(-)-N-Boc-3-pyrrolidinol (HY-W001294). (R)-(-)-N-Boc-3-pyrrolidinol is a chiral pyrrolidine derivative. After undergoing configuration inversion via the Mitsunobu reaction, (R)-(-)-N-Boc-3-pyrrolidinol can serve as a precursor for the (3S)-aryloxypyrrolidine fragment, which is used to construct key intermediates of FXa inhibitors (such as DX-9065a (HY-10722)) and various chiral drugs. (R)-(-)-N-Boc-3-pyrrolidinol can be applied in studies related to arrhythmia.
For research use only. We do not sell to patients.
- Formula: C9H13D4NO3
- Molecular Weight:191.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 109431-87-0
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Molecular Weight 191.26
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Formula C9H13D4NO3
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SMILES
O[C@@H]1CC([2H])(N(C1([2H])[2H])C(OC(C)(C)C)=O)[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Nagahara T, et al. Dibasic (amidinoaryl)propanoic acid derivatives as novel blood coagulation factor Xa inhibitors. Journal of medicinal chemistry. 1994 Apr 15;37(8):1200-7. [Content Brief]
[3]. Wang L, et al. Immobilization of growing Sphingomonas sp. HXN-200 to gelatin microspheres: efficient biotransformation of N-Cbz-pyrrolidine and N-Boc-pyrrolidine into hydroxypyrrolidine derivatives. Journal of biotechnology. 2014 Jul 20;182-183:74-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-(-)-N-Boc-3-pyrrolidinol-d4 Related Classifications
HY-W756265 Related Classifications
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Keywords
- (R)-(-)-N-Boc-3-pyrrolidinol-d4
- Isotope-Labeled Compounds
- Biochemical Assay Reagents
- Drug Intermediate
- Mitsunobu conditions
- ion channel modulating compounds
- p-hydroxybenzaldehyde
- freely suspended cells
- N-Boc-pyrrolidine
- blood coagulation factor Xa inhibitors
- N-tert-butoxycarbonyl-pyrrolidine
- ethyl 2-(4-hydroxyphenyl)-2-oxoacetate
- gelatin microsphere-immobilized Sphingomonas sp. HXN-200 cells
- methyl 2-(5-cyano-2-benzofuranyl)-3-(4-hydroxyphenyl)propanoate
- Inhibitor
- inhibitor
- inhibit