ALDH3A1 Protein, Human (sf9, His)

The ALDH3A1 protein is critical for acetaldehyde detoxification in alcohol metabolism, oxidizing medium- and long-chain aldehydes to nontoxic fatty acids. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 Protein, Human (sf9, His) is the recombinant human-derived ALDH3A1 protein, expressed by Sf9 insect cells , with N-His labeled tag.

ALDH3A1 proteins play a crucial role in detoxifying acetaldehyde derived from alcohol metabolism, participating in the oxidation of medium and long-chain aldehydes into non-toxic fatty acids. Additionally, they are implicated in the metabolism of various compounds, including corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This enzyme exhibits a preference for aromatic aldehyde substrates and constitutes approximately 50 percent of corneal epithelial soluble proteins, potentially contributing to the protection against corneal damage induced by ultraviolet light.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

Sf9 insect cells

N-His

AAH04370.1 (M1-H453)

218  [NCBI]

Full Length

MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH

Approximately 50 kDa

≥ 90%, as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at 4°C for 6 months from date of receipt. Recommend aliquoting the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.

Room temperature in continental US; may vary elsewhere.