ALDH3A1 Protein, Human (sf9, His)

The ALDH3A1 protein is critical for acetaldehyde detoxification in alcohol metabolism, oxidizing medium- and long-chain aldehydes to nontoxic fatty acids. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 Protein, Human (sf9, His) is the recombinant human-derived ALDH3A1 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ALDH3A1 Protein, Human (sf9, His) is 453 a.a., with molecular weight of ~50 kDa.

ALDH3A1 proteins play a crucial role in detoxifying acetaldehyde derived from alcohol metabolism, participating in the oxidation of medium and long-chain aldehydes into non-toxic fatty acids. Additionally, they are implicated in the metabolism of various compounds, including corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This enzyme exhibits a preference for aromatic aldehyde substrates and constitutes approximately 50 percent of corneal epithelial soluble proteins, potentially contributing to the protection against corneal damage induced by ultraviolet light.

Human

Sf9 insect cells

N-His

AAH04370.1 (M1-H453)

218  [NCBI]

Approximately 50 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.