2. 組換えタンパク質
  3. Immune Checkpoint Proteins CD Antigens
  4. Inhibitory Checkpoint Molecules Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  5. B7-2/CD86
  6. B7-2/CD86 Protein, Human (HEK293, His-Avi)

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

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製品説明

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Background

B7-2/CD86 protein functions as a negative regulator of T-cell activation by disrupting the formation of CD86 clusters. Through this interference, it modulates the T-cell response and plays a role in regulating immune activation.
Species

Human
Source

HEK293
Tag

C-Avi;C-6*His
Accession

P42081-1 (L26-P247)
Gene ID

942  [NCBI]
Molecular Construction
N-term
B7-2 (L26-P247)
Accession # P42081-1
6*His-Avi
C-term
Protein Length

Extracellular Domain
Synonyms
CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2
AA Sequence

LKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQENLVLNEVYLGKEKFDSVHSKYMGRTSFDSDSWTLRLHNLQIKDKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNITENVYINLTCSSIHGYPEPKKMSVLLRTKNSTIEYDGVMQKSQDNVTELYDVSISLSVSFPDVTSNMTIFCILETDKTRLLSSPFSIELEDPQPPPDHIP

Predicted Molecular Mass
28.2 kDa
分子量

Approximately 55-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
純度

≥ 95%, as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
ドキュメンテーション
取扱説明書 (2659 KB)

B7-2/CD86 Protein, Human (HEK293, His-Avi) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
B7-2/CD86 Protein, Human (HEK293, His-Avi)
製品番号:
HY-P78383
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