BAFFR/TNFRSF13C Protein, Mouse (HEK293, His)

BAFFR/TNFRSF13C Protein, a B-cell receptor for TNFSF13B/BAFF/BLyS, crucially supports mature B-cell survival and the overall B-cell response. Engaging with TNFSF13B, BAFFR regulates B-cell viability, ensuring the persistence of mature B-cells for an effective immune response. BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is the recombinant mouse-derived BAFFR/TNFRSF13C protein, expressed by HEK293 , with C-His labeled tag. The total length of BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is 62 a.a., with molecular weight of 15-20 kDa.

BAFFR/TNFRSF13C, a B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS, plays a crucial role in the survival of mature B-cells and the overall B-cell response. This receptor is instrumental in mediating the effects of the TNFSF13B ligand, also known as B-cell activating factor (BAFF) or B lymphocyte stimulator (BLyS). By engaging with TNFSF13B, BAFFR contributes to the regulation of B-cell viability, ensuring the persistence of mature B-cells and facilitating an effective B-cell immune response.

Immobilized Human BAFF Fc at 1 μg/mL (100 μL/well) can bind Mouse BAFFR His with a linear range of 2-63 ng/mL.

Mouse

HEK293

C-His

Q9D8D0-1 (S10-A71)

72049  [NCBI]

Partial

SQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVA

Approximately 15-20 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

≥ 90%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized a 0.22 μm filtered solution of PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.