BAFFR/TNFRSF13C Protein, Mouse (HEK293, His)
BAFFR/TNFRSF13C Protein, a B-cell receptor for TNFSF13B/BAFF/BLyS, crucially supports mature B-cell survival and the overall B-cell response. Engaging with TNFSF13B, BAFFR regulates B-cell viability, ensuring the persistence of mature B-cells for an effective immune response. BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is the recombinant mouse-derived BAFFR/TNFRSF13C protein, expressed by HEK293 , with C-His labeled tag. The total length of BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is 62 a.a., with molecular weight of 15-20 kDa.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
BAFFR/TNFRSF13C Protein, a B-cell receptor for TNFSF13B/BAFF/BLyS, crucially supports mature B-cell survival and the overall B-cell response. Engaging with TNFSF13B, BAFFR regulates B-cell viability, ensuring the persistence of mature B-cells for an effective immune response. BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is the recombinant mouse-derived BAFFR/TNFRSF13C protein, expressed by HEK293 , with C-His labeled tag. The total length of BAFFR/TNFRSF13C Protein, Mouse (HEK293, His) is 62 a.a., with molecular weight of 15-20 kDa.
Background
BAFFR/TNFRSF13C, a B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS, plays a crucial role in the survival of mature B-cells and the overall B-cell response. This receptor is instrumental in mediating the effects of the TNFSF13B ligand, also known as B-cell activating factor (BAFF) or B lymphocyte stimulator (BLyS). By engaging with TNFSF13B, BAFFR contributes to the regulation of B-cell viability, ensuring the persistence of mature B-cells and facilitating an effective B-cell immune response.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-His
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Accession
Q9D8D0-1 (S10-A71)
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Molecular Construction
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N-term
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BAFFR (S10-A71)
Accession # Q9D8D0-1 -
His
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C-term
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Protein Length
Partial Extracellular Domain
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Synonyms
TNFRSF13C; BLyS Receptor 3; TNF Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor; BAFFR; B-Cell-Activating Factor Receptor; BAFF Receptor; CD268 Antigen; BAFF-R; Prolixin; CD268; BROMIX; Tumor Necrosis Factor Receptor Superfamily, Member
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AA Sequence
SQRSRDSSVPTQCNQTECFDPLVRNCVSCELFHTPDTGHTSSLEPGTALQPQEGSALRPDVA
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Predicted Molecular Mass
8.7 kDa
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Molecular Weight
Approximately 15-20 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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