Cadherin-8 Protein, Rat (HEK293, His)
Cadherin-8, a calcium-dependent cell adhesion protein, participates in homophilic interactions, potentially aiding the sorting of diverse cell types. Its ability for preferential homophilic interaction underscores its role in mediating cell-cell adhesions and implies involvement in cellular organization and coordination. Cadherin-8 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-8 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Rat
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
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Biological Activity
Description
Cadherin-8, a calcium-dependent cell adhesion protein, participates in homophilic interactions, potentially aiding the sorting of diverse cell types. Its ability for preferential homophilic interaction underscores its role in mediating cell-cell adhesions and implies involvement in cellular organization and coordination. Cadherin-8 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-8 protein, expressed by HEK293 , with C-His labeled tag.
Background
Cadherin-8, a calcium-dependent cell adhesion protein, engages in homophilic interactions with itself in connecting cells. This characteristic underscores the potential contribution of cadherin-8, along with other cadherins, to the sorting of heterogeneous cell types. The ability to preferentially interact in a homophilic manner highlights its role in mediating cell-cell adhesions and suggests its involvement in cellular organization and coordination.
Technical Parameters
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Species Rat
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Source HEK293
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Tag C-His
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Accession
NP_445845.2 (A30-M621)
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Molecular Construction
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N-term
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Cadherin-8 (A30-M621)
Accession # NP_445845.2 -
His
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C-term
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Protein Length
Partial Extracellular Domain
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Synonyms
CDH8; Cadherin-8; Cadherin 8; Alternative Protein CDH8; Cadherin 8, Type 2; Nbla04261
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AA Sequence
APMNQAHVLTTGSPLELSRQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNISIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSM
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Predicted Molecular Mass
66.5 kDa
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Molecular Weight
Approximately 75-85 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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