Cadherin-8
Cadherin-8 (CDH8) is a classical cadherin expressed predominantly in the brain, with notable levels in hippocampus, cerebellum, and thalamus, and additional expression in kidney and testis. It mediates calcium-dependent homophilic adhesion and associates with catenins at adherens-type contacts, participating in neuronal differentiation and the organization of synaptic and dendritic structures. Cadherin-8 expression can be induced by transforming growth factor-beta in renal epithelial cells, connecting it to epithelial plasticity programs. Compared with widely expressed family members, cadherin-8 has a narrower tissue repertoire, and reduced CDH8 levels have been observed in certain carcinomas, suggesting a suppressive adhesive role.
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Cadherin-8 Recombinant Proteins (3)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
