1. Recombinant Proteins
  2. Cadherin-8 Protein, Human (HEK293, His)

Cadherin-8 Protein, Human (HEK293, His)

Cat. No.: HY-P7704
Handling Instructions

Cadherin-8 Protein, Human (HEK293, His), a recombinant human Cadherin-8 produced in HEK293 cells, has a His tag at the N-terminus. Cadherin-8 (Cdh8) is a classical type II cadherin that can bind β-catenin and has a role in the migration and growth of other neuronal cell types[1].

For research use only. We do not sell to patients.

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rHuCadherin-8, His; Cadherin-8; CDH8
Species

Human

Source

HEK 293

Accession

P55286 (A30-M621)

Gene ID

1006

Molecular Weight

Approximately 89.0 kDa

AA Sequence

APMNQSQVLMSGSPLELNSLGEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMHHHHHH

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against 20 mM PB,150 mM NaCl, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Cadherin-8 (Cdh8) is a classical type II cadherin that can bind β-catenin. Most studies examined Cdh8 expression perinatally and postnatally, when it is expressed strongly in certain layers of the cortex, hippocampus and striatum. Cdh8 has also been found to have a role in the migration and growth of other neuronal cell types[1].

Documentation
References
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Product Name:
Cadherin-8 Protein, Human (HEK293, His)
Cat. No.:
HY-P7704
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