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  5. CD200 Protein, Human (HEK293, Fc)

CD200 Protein, Human (HEK293, Fc)

Cat. No.: HY-P72887
Handling Instructions

CD200 Protein stimulates T-cell proliferation and regulates myeloid cell activity in tissues. It interacts with CD200R1 through their Ig-like domains, indicating its role in immune response modulation and maintaining cellular homeostasis. CD200 Protein, Human (HEK293, Fc) is the recombinant human-derived CD200 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD200 Protein, Human (HEK293, Fc) is 202 a.a., with molecular weight of 65-90 kDa.

For research use only. We do not sell to patients.

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Description

CD200 Protein stimulates T-cell proliferation and regulates myeloid cell activity in tissues. It interacts with CD200R1 through their Ig-like domains, indicating its role in immune response modulation and maintaining cellular homeostasis. CD200 Protein, Human (HEK293, Fc) is the recombinant human-derived CD200 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD200 Protein, Human (HEK293, Fc) is 202 a.a., with molecular weight of 65-90 kDa.

Background

CD200 Protein acts as a potent costimulator for T-cell proliferation and is implicated in regulating myeloid cell activity across various tissues. Its functional interplay with CD200R1 is facilitated through the interaction of their N-terminal Ig-like domains, suggesting a pivotal role in modulating immune responses and maintaining homeostasis within diverse cellular environments.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

P41217 (Q31-G232)

Gene ID
Molecular Construction
N-term
CD200 (Q31-G232)
Accession # P41217
hFc
C-term
Synonyms
OX-2 membrane glycoprotein; CD200; MOX1; MOX2; My033
AA Sequence

QVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKG

Molecular Weight

65-90 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD200 Protein, Human (HEK293, Fc)
Cat. No.:
HY-P72887
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