CD38 Protein, Human (HEK293, His, MALS verified)
Based on 1 Customer Validation
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Verified Bioactivity
1.Immobilized Human CD38 at 5 μg/mL (100 μL/well) can bind Anti-CD38 (HY-P9976) with a linear range of 0.1371 ng/mL.
2.Isatuximab (anti-CD38) (HY-P9976) captured on Protein A chip can bind Human CD38 with an affinity constant of 1.83 nM as determined in a SPR assay.
3.Daratumumab (HY-P9915) captured on Protein A chip can bind Human CD38 with an affinity constant of 30.5 nM as determined in a SPR assay.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-10*His
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Accession
P28907-1/NP_001766 (V43-I300)
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Gene ID952
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Molecular Construction
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N-term
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CD38 (V43-I300)
Accession # P28907-1 -
10*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CD38; NAD(+) Nucleosidase; CD38 Molecule; CD38 Antigen (P45); ADP-Ribosyl Cyclase 1; ADPRC 1; ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; 2'-Phospho-Cyclic-ADP-Ribose Transferase; Cluster Of Differentiation 38; 2'-Phospho-ADP-Ribosyl Cyclase; CADPR Hydrolase 1; Cyclic ADP-Ribose Hydrolase 1; CD38 Antigen; CADPR1; ADPRC1; 2'-Phospho-ADP-Ribosyl Cyclase/2'-Phospho-Cyclic-ADP-Ribose Transferase; T10
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AA Sequence
VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
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Predicted Molecular Mass
31.2 kDa
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Molecular Weight
Approximately 38-48 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation. Approximately 35-45 kDa, verified by SEC-MALS.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.; ≥ 95% as determined by SEC-MALS.
Product Properties
Lyophilized powder
Lyophilized from a 0.22 μm filtered solution of 50 mM MES, 100 mM NaCl, pH 6.5, 8% trehalose.
<0.01 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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