CD97 Protein, Human (HEK293, His)

CD97, a receptor crucial for leukocyte migration, participates in adhesion and signaling during early leukocyte activation. Forming a heterodimer with a large extracellular alpha subunit and a seven-transmembrane beta subunit, CD97 interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) specifically engages with chondroitin sulfate, showcasing its diverse roles in cellular processes. CD97 Protein, Human (HEK293, His) is the recombinant human-derived CD97 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD97 Protein, Human (HEK293, His) is 378 a.a., with molecular weight of 60-82 kDa.

CD97, a receptor with potential involvement in both adhesion and signaling processes during early leukocyte activation, plays a crucial role in facilitating leukocyte migration. This receptor forms a heterodimer, comprising a large extracellular alpha subunit non-covalently linked to a seven-transmembrane beta subunit. CD97 interacts with complement decay-accelerating factor (DAF) and the largest isoform (isoform 1) specifically engages with chondroitin sulfate, highlighting its diverse interactions in cellular processes.

Human

HEK293

C-His

P48960-2/NP_001775.2 (Q21-Q398)

976  [NCBI]

QDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQ

60-82 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.The protein migrates as a 60-82 kDa band under reducing SDS-PAGE due to glycosylation.

<1 EU/μg, determined by LAL method.