CNT3 Protein, Human (sf9, Strep, His)
CNT3 Protein, Human (sf9, Strep, His) is the recombinant human-derived CNT3, expressed by sf9 insect cells , with Strep, His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Biological Activity
Description
CNT3 Protein, Human (sf9, Strep, His) is the recombinant human-derived CNT3, expressed by sf9 insect cells , with Strep, His labeled tag.
Background
CNT3 is a sodium-dependent, pyrimidine- and purine-selective transporter involved in the homeostasis of endogenous nucleosides. It exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib), with marked transport of both thymidine and inosine, and employs a 2:1 sodium/nucleoside ratio. Additionally, CNT3 transports uridine, gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin, and 3-deazauridine. by similar: It is also involved in the transport of nucleoside analogs such as gemcitabine and AZT.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Strep;His
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Accession
Q9HAS3-1 (M70-F691)
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Gene ID64078
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Protein Length
Partial
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Synonyms
SLC28A3; Concentrative Na(+)-Nucleoside Cotransporter 3; Solute Carrier Family 28 Member 3; Concentrative Na+-Nucleoside Cotransporter; CNT3; HCNT3; Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3; CNT 3; Solute Carrier Family 2
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AA Sequence
MEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLRHIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLSPGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFSKYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFGEKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVASGNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTASVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANIAVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVARLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANIGSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHVLENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTFNCNGISNTF
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Predicted Molecular Mass
71.4 kDa
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)