CTRC Protein, Human (HEK293, His)

CTRC proteins critically regulate trypsinogen and procarboxypeptidase, precisely cleaving their zymogen precursors to influence activation and degradation. Its chymotrypsin-type protease activity helps control enzyme processing. CTRC Protein, Human (HEK293, His) is the recombinant human-derived CTRC protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CTRC Protein, Human (HEK293, His) is 252 a.a., with molecular weight of 33-40 kDa.

The CTRC protein plays a crucial role in the regulation of trypsinogens and procarboxypeptidases by precisely targeting specific cleavage sites within their zymogen precursors, thereby influencing their activation and degradation processes. With its chymotrypsin-type protease activity, CTRC contributes to the controlled processing of these enzymes. Additionally, it exhibits hypocalcemic activity, suggesting its involvement in calcium homeostasis or signaling pathways. The multifaceted functions of CTRC underscore its significance in modulating key proteolytic events, with implications for various physiological processes and potential relevance in pathological conditions.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

Q99895 (C17-L268)

11330  [NCBI]

CGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL

33-40 kDa

Greater than 95% as determined by reducing SDS-PAGE

Solution.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.