DcR3/TNFRSF6B Protein, Human (HEK293, hFc)
DcR3/TNFRSF6B Protein, Human (HEK293, hFc) is the recombinant human-derived DcR3/TNFRSF6B protein, expressed by HEK293, with C-hFc tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
DcR3/TNFRSF6B Protein, Human (HEK293, hFc) is the recombinant human-derived DcR3/TNFRSF6B protein, expressed by HEK293, with C-hFc tag.
Background
DcR3/TNFRSF6B is a decoy receptor capable of neutralizing cytotoxic ligands TNFS14/LIGHT, TNFSF15, and TNFSF6/FASL, thereby providing anti-apoptotic protection.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-hFc
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Accession
O95407 (V30-H300)
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Gene ID8771
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Molecular Construction
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N-term
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TNF6B (V30-H300)
Accession # O95407 -
hFc
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
TNFRSF6B; Alternative Protein TNFRSF6B; TNF Receptor Superfamily Member 6b; Decoy Receptor 3 Variant 2; DcR3; Decoy Receptor 3 Variant 1; TR6; Decoy Receptor 3; M68; DJ583P15.1.1; Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy; M68E; Tumor N
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AA Sequence
VAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
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Predicted Molecular Mass
56.2 kDa
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Molecular Weight
Approximately 60-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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