EMMPRIN/CD147 Protein, Canine (HEK293, His)
EMMPRIN/CD147 Protein, Canine (HEK293, His) is the recombinant canine-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.
- Species: Canine
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
EMMPRIN/CD147 Protein, Canine (HEK293, His) is the recombinant canine-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.
Background
EMMPRIN/CD147 is essential for normal retinal maturation and development (By similarity). It acts as a retinal cell surface receptor for NXNL1 and plays a critical role in NXNL1-mediated survival of retinal cone photoreceptors. In association with the glucose transporter SLC16A1/GLUT1 and NXNL1, it promotes retinal cone survival by enhancing aerobic glycolysis and accelerating glucose uptake into photoreceptors. Additionally, it may function as a potent stimulator of IL6 secretion in multiple cell lines, including monocytes.
Technical Parameters
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Species Canine
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Source HEK293
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Tag C-8*His
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Accession
XP_533964 (A22-R205)
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Protein Length
Partial
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AA Sequence
AGSEILTSVEDIGSKIRLTCSLNRSTTEITGHRWVKGDRVLKEDTFPDPKTEYEVDSDERSGEYSCIFLPELLGKSSIEVRGLPNIKAVKKSEHATERETVVLGCRSDSFPPVTDWVWYKVESSGDQVISNSSQSKFLVVSSETKTELRISNLDLETDPGKYVCNGTNSEGTSQAVIVLRVRNR
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Predicted Molecular Mass
21.5 kDa
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Molecular Weight
Approximately 30-45 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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