Ephrin-B2/EFNB2 Protein, Rat (HEK293, His)

Ephrin-B2, also known as EFNB2, is a protein that plays a crucial role in cellular communication and tissue development. Belonging to the ephrin family, Ephrin-B2 is a transmembrane protein that acts as both a ligand and a receptor, mediating bidirectional signaling events. Its primary function is to interact with Eph receptors on neighboring cells, initiating a cascade of intracellular signals that regulate various cellular processes, including cell adhesion, migration, and tissue patterning. Ephrin-B2 is particularly implicated in angiogenesis, the formation of new blood vessels, where it governs endothelial cell behavior and influences vascular development. Additionally, it has been associated with diverse physiological and pathological processes, such as neuronal guidance, immune response, and cancer progression. Understanding the intricate functions of Ephrin-B2 is crucial for unraveling its therapeutic potential in various medical contexts.