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  4. Meprin alpha/MEP1A Protein, Human (HEK293, His)

Meprin alpha/MEP1A Protein, Human (HEK293, His)

Cat. No.: HY-P77083
Handling Instructions

Meprin alpha (MEP1A) protein functions as a metalloendopeptidase in the membrane. It is found in structures like the gut and metanephros. MEP1A primarily expresses in the adult kidney and large intestine, indicating potential tissue-specific functions. Meprin alpha/MEP1A Protein, Human (HEK293, His) is the recombinant human-derived Meprin alpha/MEP1A protein, expressed by HEK293 , with C-His labeled tag. The total length of Meprin alpha/MEP1A Protein, Human (HEK293, His) is 580 a.a., with molecular weight of ~80 kDa.

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Description

Meprin alpha (MEP1A) protein functions as a metalloendopeptidase in the membrane. It is found in structures like the gut and metanephros. MEP1A primarily expresses in the adult kidney and large intestine, indicating potential tissue-specific functions. Meprin alpha/MEP1A Protein, Human (HEK293, His) is the recombinant human-derived Meprin alpha/MEP1A protein, expressed by HEK293 , with C-His labeled tag. The total length of Meprin alpha/MEP1A Protein, Human (HEK293, His) is 580 a.a., with molecular weight of ~80 kDa.
Background

Meprin alpha (MEP1A) protein is predicted to exhibit metalloendopeptidase activity and is primarily located in the membrane. It is expressed in various structures, including the gut and metanephros. The expression of MEP1A is notably biased, with higher expression observed in the adult kidney and large intestine, suggesting potential roles in these tissues.
Species

Human
Source

HEK293
Tag

C-His
Accession

Q16819 (V22-Q601)
Gene ID
Molecular Construction
N-term
MEP1A (V22-Q601)
Accession # Q16819
His
C-term
Synonyms
Meprin A subunit alpha; Endopeptidase-2; PABA peptide hydrolase; PPH alpha
Molecular Weight

Approximately 80 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Meprin alpha/MEP1A Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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