MPIF-1/CCL23 Protein, Human (99a.a, HEK293, His)
MPIF-1/CCL23 Protein, Human (99a.a, HEK293, His) is the recombinant human-derived MPIF-1/CCL23 protein, expressed by HEK293, with N-His tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
MPIF-1/CCL23 Protein, Human (99a.a, HEK293, His) is the recombinant human-derived MPIF-1/CCL23 protein, expressed by HEK293, with N-His tag.
Background
CCL23 exhibits chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not activated lymphocytes. It inhibits the proliferation of myeloid progenitor cells in colony formation assays and can bind both heparin and CCR1. The truncated forms CCL23(19-99), CCL23(22-99), CCL23(27-99), and CCL23(30-99) show stronger chemoattractant potency than full-length CCL23. by similar: Other chemokines like CCL3 and CCL5 also signal through CCR1, though their target cell profiles may differ.
Technical Parameters
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Species Human
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Source HEK293
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Tag N-His
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Accession
P55773-1 (R22-N120)
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Gene ID6368
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Molecular Construction
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N-term
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His
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CCL23 (R22-N120)
Accession # P55773-1 -
C-term
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Protein Length
Full Length of C-C motif chemokine 23 Chain
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Synonyms
CCL23; C-C Motif Chemokine 23; Prev. SCYA23; Small-Inducible Cytokine A23; MPIF-1; C6 Beta-Chemokine; MIP-3; CK-BETA-8; Ckb-8; CK-Beta-8; CKb8; Ckb-8-1; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 23; Hmrp-2a; Myeloid Progenitor Inhibitory Fact
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AA Sequence
RVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN
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Predicted Molecular Mass
13.3 kDa
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Molecular Weight
Approximately 12-17 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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