1. Recombinant Proteins
  2. CAR-T Related Proteins Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. Nectin-4
  6. Nectin-4 Protein, Cynomolgus (HEK293, His)

Nectin-4 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P70188
Handling Instructions

Nectin-4 protein is an important member of the Nectin family and plays a vital role in cell adhesion and signaling, thereby affecting physiological functions. Its role in mediating cell-cell interactions emphasizes its importance in tissue organization. Nectin-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Nectin-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Nectin-4 Protein, Cynomolgus (HEK293, His) is 318 a.a., with molecular weight of 38-50 kDa.

For research use only. We do not sell to patients.

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Description

Nectin-4 protein is an important member of the Nectin family and plays a vital role in cell adhesion and signaling, thereby affecting physiological functions. Its role in mediating cell-cell interactions emphasizes its importance in tissue organization. Nectin-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Nectin-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Nectin-4 Protein, Cynomolgus (HEK293, His) is 318 a.a., with molecular weight of 38-50 kDa.

Background

The Nectin-4 Protein is an integral member of the nectin family, contributing significantly to cell adhesion and signaling processes. As part of this family, Nectin-4 plays a key role in mediating cell-cell interactions, impacting various physiological and developmental functions. Its involvement in cell adhesion suggests implications for tissue organization and maintenance. Additionally, Nectin-4 has gained attention for its role in cancer, particularly in facilitating tumor cell invasion and metastasis. By belonging to the nectin family, Nectin-4 Protein underscores its importance in fundamental cellular processes and its potential significance as a therapeutic target in various pathological conditions.

Species

Cynomolgus

Source

HEK293

Tag

C-6*His

Accession

L0N6D9 (G32-S349)

Gene ID

102127936  [NCBI]

Molecular Construction
N-term
Nectin-4 (G32-S349)
Accession # L0N6D9
6*His
C-term
Synonyms
rCynPoliovirus receptor-related protein 4-like/Nectin-4, His; PVRL4; Nectin-4; Ig superfamily receptor LNIR; Poliovirus receptor-related protein 4; PRR4; LNIR
AA Sequence

GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARADAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHVGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSAS

Molecular Weight

38-50 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Nectin-4 Protein, Cynomolgus (HEK293, His)
Cat. No.:
HY-P70188
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