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  3. OPN4 Protein, Rat (Cell-Free, His)

OPN4 Protein, Rat (Cell-Free, His)

Cat. No.: HY-P702401
Handling Instructions

OPN4 Protein, a photoreceptor with affinity for cis-retinaldehydes, crucially mediates light responses like the pupillary reflex and photoentrainment. Its multifaceted role includes potential participation in optokinetic visual tracking response. Moreover, OPN4 may regulate retinal hyaloid vessel growth, emphasizing its significance in intricate aspects of ocular physiology. OPN4 Protein, Rat (Cell-Free, His) is the recombinant rat-derived OPN4 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of OPN4 Protein, Rat (Cell-Free, His) is 474 a.a., with molecular weight of 53.9 kDa.

For research use only. We do not sell to patients.

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Description

OPN4 Protein, a photoreceptor with affinity for cis-retinaldehydes, crucially mediates light responses like the pupillary reflex and photoentrainment. Its multifaceted role includes potential participation in optokinetic visual tracking response. Moreover, OPN4 may regulate retinal hyaloid vessel growth, emphasizing its significance in intricate aspects of ocular physiology. OPN4 Protein, Rat (Cell-Free, His) is the recombinant rat-derived OPN4 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of OPN4 Protein, Rat (Cell-Free, His) is 474 a.a., with molecular weight of 53.9 kDa.

Background

OPN4, a photoreceptor with an affinity for cis-retinaldehydes, plays a pivotal role in various light-mediated responses, including the pupillary reflex, photoentrainment, and other non-image forming reactions. Its involvement extends to potential participation in the optokinetic visual tracking response, showcasing its multifaceted role in visual processes. Additionally, OPN4 may contribute to the regulation of retinal hyaloid vessel growth and regression, further emphasizing its significance in orchestrating intricate aspects of ocular physiology.

Species

Rat

Source

E. coli Cell-free

Tag

N-10*His

Accession

Q8R456 (M1-M474)

Gene ID

192223

Molecular Construction
N-term
10*His
OPN4 (M1-M474)
Accession # Q8R456
C-term
Synonyms
Melanopsin; Opsin-4
AA Sequence

MNSPSESRVPSSLTQDPSFTASPALLQGIWNSTQNISVRVQLLSVSPTTPGLQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSLYKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRAAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGQKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSHDLEDGEVKAPSSPQEQKSKTPKTKRHLPSLDRRM

Molecular Weight

53.9 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

OPN4 Protein, Rat (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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OPN4 Protein, Rat (Cell-Free, His)
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HY-P702401
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