PGLYRP2/PGRP-L Protein, Human (P.pastoris, His)

The PGLYRP2/PGRP-L protein is thought to act as a scavenger and may degrade bioactive peptidoglycan (PGN) into inactive fragments. Unlike direct bacteriolytic activity, PGLYRP2/PGRP-L appears to be primarily involved in modifying PGN structure, possibly as part of the host's defense against bacterial infection. PGLYRP2/PGRP-L Protein, Human (P.pastoris, His) is the recombinant human-derived PGLYRP2/PGRP-L protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of PGLYRP2/PGRP-L Protein, Human (P.pastoris, His) is 555 a.a., with molecular weight of ~72 kDa.

PGLYRP2/PGRP-L Protein is postulated to function in a scavenger role, potentially contributing to the degradation of biologically active peptidoglycan (PGN) into biologically inactive fragments. Unlike direct bacteriolytic activities, PGLYRP2/PGRP-L seems to be primarily involved in modifying the structure of PGN, possibly as part of the host's defense mechanisms against bacterial infections. The precise molecular pathways through which PGLYRP2/PGRP-L exerts its scavenger function and its implications in immune responses warrant further investigation to unravel its specific contributions to the intricate interplay between host and microbial elements.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

P. pastoris

N-6*His

Q96PD5 (22S-576Q)

114770  [NCBI]

SLPLLMDSVIQALAELEQKVPAAKTRHTASAWLMSAPNSGPHNRLYHFLLGAWSLNATELDPCPLSPELLGLTKEVARHDVREGKEYGVVLAPDGSTVAVEPLLAGLEAGLQGRRVINLPLDSMAAPWETGDTFPDVVAIAPDVRATSSPGLRDGSPDVTTADIGANTPDATKGCPDVQASLPDAKAKSPPTMVDSLLAVTLAGNLGLTFLRGSQTQSHPDLGTEGCWDQLSAPRTFTLLDPKASLLTMAFLNGALDGVILGDYLSRTPEPRPSLSHLLSQYYGAGVARDPGFRSNFRRQNGAALTSASILAQQVWGTLVLLQRLEPVHLQLQCMSQEQLAQVAANATKEFTEAFLGCPAIHPRCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGDIGYSFVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALPTEAALRTVRDTLPSCAVRAGLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHFTATVKPRPARSVSKRSRREPPPRTLPATDLQ

Approximately 72 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.