PIK3IP1 Protein, Human (HEK293, His)

PIK3IP1 protein acts as a potent negative regulator of phosphatidylinositol 3-kinase (PI3K) activity in the liver. It crucially modulates the PI3K signaling pathway, exerting inhibitory control over cellular processes influenced by PI3K. PIK3IP1's regulatory function emphasizes its significance in finely tuning intracellular signaling, particularly in hepatic processes where PI3K plays a central role in various cellular functions. PIK3IP1 Protein, Human (HEK293, His) is the recombinant human-derived PIK3IP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PIK3IP1 Protein, Human (HEK293, His) is 147 a.a., with molecular weight of 25-37 kDa.

PIK3IP1 protein functions as a potent negative regulator of phosphatidylinositol 3-kinase (PI3K) activity in the liver. Through its regulatory role, PIK3IP1 plays a crucial part in modulating the PI3K signaling pathway, exerting inhibitory control over the cellular processes influenced by PI3K activity. This regulatory function highlights the significance of PIK3IP1 in finely tuning intracellular signaling events, particularly in the context of hepatic processes where PI3K plays a central role in various cellular functions.

Human

HEK293

C-6*His

Q96FE7 (S22-T168)

113791  [NCBI]

SGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPETTSQALPAFTTEIQEASEGPGADEVQVFAPANALPARSEAAAVQPVIGISQRVRMNSKEKKDLGT

25-37 KDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.