Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His)

Semaphorin-3A/SEMA3A Protein guides growth cones and is implicated in sensory projection patterning, selectively repelling axons that terminate dorsally. It contributes to olfactory system development and neuronal control of puberty. SEMA3A interacts with PXND1, although the exact nature of this interaction is unspecified. Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Semaphorin-3A/SEMA3A protein, expressed by HEK293, with N-His labeled tag. The total length of Semaphorin-3A/SEMA3A Protein, Mouse (HEK293, His) is 752 a.a., with molecular weight of ~86.6 kDa.

The Semaphorin-3A/SEMA3A protein plays a crucial role in guiding growth cones. It is believed to participate in patterning sensory projections by selectively repelling axons that typically terminate dorsally. SEMA3A is also involved in the development of the olfactory system and contributes to neuronal control of puberty. Additionally, it interacts with PXND1, although the exact nature of this interaction is not specified.

Mouse

HEK293

N-His

O08665 (Y21-V772)

20346  [NCBI]

Approximately 86.6 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 100 mM L-Arginine, 100 mM glutamic acid, pH 8.5. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.