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  4. Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His)

Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His)

Cat. No.: HY-P78034
Handling Instructions

Semaphorin-4B (SEMA4B) protein inhibits axonal extension by emitting local signals that define inaccessible territories for growing axons. It interacts with the GIPC PDZ domain, regulating axonal guidance and territorial specificity during neural development. Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His) is the recombinant mouse-derived Semaphorin-4B/SEMA4B protein, expressed by HEK293 , with C-His labeled tag. The total length of Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His) is 673 a.a., with molecular weight of 78-83 kDa.

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Description

Semaphorin-4B (SEMA4B) protein inhibits axonal extension by emitting local signals that define inaccessible territories for growing axons. It interacts with the GIPC PDZ domain, regulating axonal guidance and territorial specificity during neural development. Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His) is the recombinant mouse-derived Semaphorin-4B/SEMA4B protein, expressed by HEK293 , with C-His labeled tag. The total length of Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His) is 673 a.a., with molecular weight of 78-83 kDa.
Background

Semaphorin-4B (SEMA4B) protein plays a crucial role in inhibiting axonal extension by emitting local signals that define territories as inaccessible for growing axons. Its mechanism involves interaction with the GIPC PDZ domain, contributing to the regulation of axonal guidance and territorial specificity during neural development.
Species

Mouse
Source

HEK293
Tag

C-His
Accession

Q62179 (L31-E703)
Gene ID

20352  [NCBI]
Molecular Construction
N-term
SEMA4B (L31-E703)
Accession # Q62179
His
C-term
Synonyms
Semaphorin-4B; Semaphorin-C; SEMA4B; KIAA1745; SEMAC; MGC131831; SemC
Molecular Weight

78-83 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Semaphorin-4B/SEMA4B Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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