2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. Dendritic Cell CD Proteins Siglec
  5. Siglec-5/CD170
  6. Siglec-5 Protein, Human (HEK293, His-Avi)

Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

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제품 설명

Siglec-5 Protein, a putative adhesion molecule, participates in sialic-acid dependent cellular binding, showing equal affinity for alpha-2,3-linked and alpha-2,6-linked sialic acid. Its sialic acid recognition site may be masked through cis interactions with sialic acids on the same cell surface. Siglec-5 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Background

Siglec-5 protein, a putative adhesion molecule, is implicated in sialic-acid dependent cellular binding, displaying equal affinity for both alpha-2,3-linked and alpha-2,6-linked sialic acid. Notably, the sialic acid recognition site of Siglec-5 may be subject to masking through cis interactions with sialic acids on the same cell surface.
Species

Human
Source

HEK293
Tag

C-Avi;C-8*His
Accession

O15389 (E17-T434)
Gene ID
Molecular Construction
N-term
Siglec-5 (E17-T434)
Accession # O15389
8*His-Avi
C-term
Protein Length

Partial
Synonyms
CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2
AA Sequence

EKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRSNLGT

Predicted Molecular Mass
49.3 kDa
분자량

Approximately 68-78 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

Siglec-5 Protein, Human (HEK293, His-Avi) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Siglec-5 Protein, Human (HEK293, His-Avi)
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