SIRP beta 1 Protein, Human (isoform 3, HEK293, His-Avi)

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, crucially negatively regulates receptor tyrosine kinase-coupled signaling processes. It modulates cellular responses to stimuli like cell adhesion, growth factors, or insulin, contributing to maintaining cellular homeostasis and finely tuning signaling pathways associated with receptor tyrosine kinases. SIRP beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is the recombinant human-derived SIRP Beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, plays a crucial role in negatively regulating receptor tyrosine kinase-coupled signaling processes. This receptor modulates cellular responses induced by various stimuli, including cell adhesion, growth factors, or insulin. Through its regulatory functions, SIRP Beta 1 contributes to maintaining cellular homeostasis and finely tuning the activation of signaling pathways associated with receptor tyrosine kinases.

Human

HEK293

C-Avi;C-6*His

Q5TFQ8 (E30-L371)

10326  [NCBI]

Extracellular Domain

EEELQVIQPDKSISVAAGESATLHCTVTSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPADAGTYYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAPGPALASAAPL

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by Bis-Tris PAGE.

<1 EU/μg, determined by LAL method.