1. Recombinant Proteins
  2. CD Antigens Receptor Proteins Biotinylated Proteins
  3. Macrophage CD Proteins Dendritic Cell CD Proteins Cell Adhesion Molecules (CAMs)
  4. SIRP beta 1/CD172b Immunoglobulin-like Cell Adhesion Molecules
  5. Signal Regulatory Protein Beta 1
  6. SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi)

SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi)

Cat. No.: HY-P77838
Handling Instructions

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, crucially negatively regulates receptor tyrosine kinase-coupled signaling processes. It modulates cellular responses to stimuli like cell adhesion, growth factors, or insulin, contributing to maintaining cellular homeostasis and finely tuning signaling pathways associated with receptor tyrosine kinases. SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is the recombinant human-derived SIRP Beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is 342 a.a., with molecular weight of 60-70 kDa.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, crucially negatively regulates receptor tyrosine kinase-coupled signaling processes. It modulates cellular responses to stimuli like cell adhesion, growth factors, or insulin, contributing to maintaining cellular homeostasis and finely tuning signaling pathways associated with receptor tyrosine kinases. SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is the recombinant human-derived SIRP Beta 1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi) is 342 a.a., with molecular weight of 60-70 kDa.

Background

SIRP Beta 1 Protein, an immunoglobulin-like cell surface receptor, plays a crucial role in negatively regulating receptor tyrosine kinase-coupled signaling processes. This receptor modulates cellular responses induced by various stimuli, including cell adhesion, growth factors, or insulin. Through its regulatory functions, SIRP Beta 1 contributes to maintaining cellular homeostasis and finely tuning the activation of signaling pathways associated with receptor tyrosine kinases.

Species

Human

Source

HEK293

Tag

C-Avi;C-His

Accession

Q5TFQ8 (E30-L371)

Gene ID
Molecular Construction
N-term
SIRP Beta 1 (E30-L371)
Accession # Q5TFQ8
His-Avi
C-term
Synonyms
SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a
Molecular Weight

60-70 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SIRP Beta 1 Protein, Human (isoform 3, HEK293, His-Avi)
Cat. No.:
HY-P77838
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