SIRP gamma Protein, Human (HEK293, His-Avi)

SIRP gamma Protein, a probable immunoglobulin-like cell surface receptor, mediates cell-cell adhesion by binding with CD47. This interaction enhances antigen-specific T-cell proliferation and provides costimulatory signals for T-cell activation, highlighting SIRP gamma's role in modulating immune responses. The intricate interactions with CD47 underscore SIRP gamma's significance as a cell surface receptor, crucial in cellular adhesion and regulating T-cell activation pathways. SIRP gamma Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293, with C-His, C-Avi labeled tag. The total length of SIRP gamma Protein, Human (HEK293, His-Avi) is 332 a.a., with molecular weight of 47-49 kDa.

The SIRP gamma protein emerges as a probable immunoglobulin-like cell surface receptor, demonstrating its role in mediating cell-cell adhesion upon binding with CD47. This interaction is pivotal in enhancing antigen-specific T-cell proliferation and providing costimulatory signals for T-cell activation. As a result, SIRP gamma engages with CD47 on antigen-presenting cells, highlighting its involvement in modulating immune responses. The intricate interactions between SIRP gamma and CD47 underscore its significance as a cell surface receptor, playing a crucial role in cellular adhesion and the regulation of T-cell activation pathways.

Human

HEK293

C-His;C-Avi

Q9P1W8 (E29-P360)

55423  [NCBI]

47-49 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.