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SNTG1 Protein, Human (Myc, His)

Cat. No.: HY-P71635
Handling Instructions

SNTG1 acts as an adapter protein that binds and potentially organizes various proteins, serving as a link between the receptor and the actin cytoskeleton or dystrophin glycoprotein complex. It may modulate the subcellular distribution of diacylglycerol kinase-zeta and contribute to the rapid inactivation of diacylglycerol upon receptor activation. SNTG1 Protein, Human (Myc, His) is the recombinant human-derived SNTG1 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of SNTG1 Protein, Human (Myc, His) is 517 a.a., with molecular weight of ~63.0 kDa.

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Description

SNTG1 acts as an adapter protein that binds and potentially organizes various proteins, serving as a link between the receptor and the actin cytoskeleton or dystrophin glycoprotein complex. It may modulate the subcellular distribution of diacylglycerol kinase-zeta and contribute to the rapid inactivation of diacylglycerol upon receptor activation. SNTG1 Protein, Human (Myc, His) is the recombinant human-derived SNTG1 protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of SNTG1 Protein, Human (Myc, His) is 517 a.a., with molecular weight of ~63.0 kDa.

Background

SNTG1 functions as an adapter protein with the capacity to bind and likely organize the subcellular localization of diverse proteins, potentially serving as a link between various receptors and the actin cytoskeleton as well as the dystrophin glycoprotein complex. It may play a role in regulating the subcellular distribution of diacylglycerol kinase-zeta to facilitate the prompt inactivation of diacylglycerol following receptor activation. Notably, isoform 1 of SNTG1, in contrast to isoform 2, engages in interactions with the dystrophin protein DMD and its related counterparts DTNA and DTNB. Additionally, SNTG1 forms an interaction with DGKZ, suggesting its involvement in modulating the cellular dynamics of key signaling molecules and structural components.

Species

Human

Source

E. coli

Tag

N-His;C-Myc

Accession

Q9NSN8 (1M-517T)

Gene ID
Molecular Construction
N-term
10*His
SNTG1 (1M-517T)
Accession # Q9NSN8
C-term
Synonyms
G1SYN; Gamma 1 syntrophin; SNTG 1; Sntg1; SNTG1_HUMAN; SYN 4; SYN4; Synotrophin gamma 1; Syntrophin 4; Syntrophin gamma 1; Syntrophin-4
AA Sequence

MDFRTACEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPGTDLSRQNAFQVIAVDGVCTGIIQCLSAEDCVDWLQAIATNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQDPLQDRVYSPTFLALRGSCLYKFLAPPVTTWDWTRAEKTFSVYEIMCKILKDSDLLDRRKQCFTVQSESGEDLYFSVELESDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFICFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQATASTAASSATTSKAKYTT

Molecular Weight

Approximately 63.0 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SNTG1 Protein, Human (Myc, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SNTG1 Protein, Human (Myc, His)
Cat. No.:
HY-P71635
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