SPARCL1 Protein, Mouse (283a.a, HEK293, His)
Based on 1 Customer Validation
SPARCL1 protein has important functions such as calcium ion, collagen and extracellular matrix binding. SPARCL1 mainly plays a role in glutamatergic synaptic membrane adhesion. SPARCL1 Protein, Mouse (283a.a, HEK293, His) is the recombinant mouse-derived SPARCL1 protein, expressed by HEK293 , with N-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
SPARCL1 protein has important functions such as calcium ion, collagen and extracellular matrix binding. SPARCL1 mainly plays a role in glutamatergic synaptic membrane adhesion. SPARCL1 Protein, Mouse (283a.a, HEK293, His) is the recombinant mouse-derived SPARCL1 protein, expressed by HEK293 , with N-His labeled tag.
Background
SPARCL1 protein is a multifunctional molecule with calcium ion, collagen and extracellular matrix binding activities. It is mainly localized at glutamatergic synapses and participates in the synaptic membrane adhesion process. SPARCL1 is widely expressed in multiple systems, including cardiovascular, central nervous, male reproductive, respiratory and sensory organ systems, and is particularly highly expressed in adult bladder and cortex, suggesting that it plays a key role in these tissues. The protein is highly conserved in evolution, and the existence of its human homolog SPARC like 1 further confirms its functional importance.
Verified Bioactivity
Measured by its ability to inhibit the cell growth of Mv-1-Lu mink lung epithelial cells. The ED50 for this effect is typically 1.0-4.0 μg/mL.
MCE Validation Data
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Purity - SDS-PAGE
Purity - SDS-PAGE
Technical Parameters
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Species Mouse
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Source HEK293
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Tag N-His
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Accession
NP_034227.3 (Y368-F650)
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Molecular Construction
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N-term
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His
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SPARCL1 (Y368-F650)
Accession # NP_034227.3 -
C-term
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Protein Length
Partial
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Synonyms
SPARCL1; Hevin; SPARC Like 1; PIG33; SPARC-Like Protein 1; Proliferation-Inducing Protein 33; MAST9; SPARC-Like 1 (Mast9, Hevin); High Endothelial Venule Protein; SPARC-Like 1 (Hevin); MAST 9; SC1
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AA Sequence
YLKYGGGEETTTGESENRREAADNQEAKKAESSPNAEPSDEGNSREHSAGSCTNFQCKRGHICKTDPQGKPHCVCQDPETCPPAKILDQACGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPACTDFEVAQFPLRMRDWLKNILMQLYEPNPKHGGYLNEKQRSKVKKIYLDEKRLLAGDHPIELLLRDFKKNYHMYVYPVHWQFNELDQHPADRILTHSELAPLRASLVPMEHCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLF
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Predicted Molecular Mass
34.8 kDa
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Molecular Weight
Approximately 38-48 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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