STC2/Stanniocalcin-2 Protein, Human (HEK293, Fc)

STC2/Stanniocalcin-2 Protein plays a vital role in maintaining calcium and phosphate homeostasis and exhibits strong anti-hypocalcemic effects. As a homodimer with disulfide linkages, STC2 plays a crucial structural role in regulating calcium and phosphate balance. This unique property emphasizes the pivotal role of STC2 in preserving the delicate equilibrium of essential minerals in the body. STC2/Stanniocalcin-2 Protein, Human (HEK293, Fc) is the recombinant human-derived STC2/Stanniocalcin-2 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

STC2/Stanniocalcin-2 Protein plays a vital role in maintaining calcium and phosphate homeostasis and exhibits strong anti-hypocalcemic effects. As a homodimer with disulfide linkages, STC2 plays a crucial structural role in regulating calcium and phosphate balance. This unique property emphasizes the pivotal role of STC2 in preserving the delicate equilibrium of essential minerals in the body. STC2/Stanniocalcin-2 Protein, Human (HEK293, Fc) is the recombinant human-derived STC2/Stanniocalcin-2 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

STC2, a crucial player in calcium and phosphate homeostasis, exerts a potent anti-hypocalcemic action. Operating as a homodimer with disulfide linkages, STC2 showcases its structural significance in mediating regulatory responses related to the balance of calcium and phosphate levels. This distinctive property underscores the pivotal role of STC2 in maintaining the intricate equilibrium of essential minerals within the physiological milieu.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-hFc
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • STC2 (T25-R302)
      Accession # O76061
    • hFc
    • C-term
  • Protein Length

    Full Length of Mature Protein

  • Synonyms

    STC2; Stanniocalcin-Related Protein; Stanniocalcin 2; STC-Related Protein; STC-2; STCRP; Stanniocalcin-2

  • AA Sequence

    TDATNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR

  • Predicted Molecular Mass

    57.7 kDa

  • Molecular Weight

    Approximately 63 kDa, based on SDS-PAGE under reducing conditions.

  • Glycosylation

    Yes

  • Purity

    ≥ 85%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
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Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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