Remdesivir de(ethylbutyl 2-aminopropanoate)
Remdesivir de(ethylbutyl 2-aminopropanoate) is an impurity of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
For research use only. We do not sell to patients.
- CAS No.: 2607871-93-0
- Formula: C18H18N5O7P
- Molecular Weight:447.34
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
-
CAS No. 2607871-93-0
-
Molecular Weight 447.34
-
Formula C18H18N5O7P
-
SMILES
N#C[C@@]([C@@H]([C@@H]1O)O)(C2=CC=C3N2N=CN=C3N)O[C@@H]1CO[P](OC4=CC=CC=C4)(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2):e00221-18. [Content Brief]
[2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)