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Cat. No.: HY-12216S

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MGL-3196¹³C₃,¹⁵N; VIA-3196¹³C₃,¹⁵N

(Synonyms: MGL-3196¹³C₃,¹⁵N; VIA-3196¹³C₃,¹⁵N)

Resmetirom-¹³C₃,¹⁵N (MGL-3196-¹³C₃,¹⁵N) is the ¹³C- and ¹⁵N-labeled Resmetirom (HY-12216). Resmetirom (MGL-3196) is a highly selective and orally active thyroid hormone receptor β (THR-β) agonist with an EC₅₀ value of 0.21 μM. Resmetirom can be used for the study of noncirrhotic nonalcoholic steatohepatitis.

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Formule: C₁₄¹³C₃H₁₂Cl₂N₅¹⁵NO₄
Masse moléculaire:439.19

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MGL-3196¹³C₃,¹⁵N; VIA-3196¹³C₃,¹⁵N Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Application
Chemical Information
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Activité biologique

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 920509-32-6
Masse moléculaire 439.19
Formule C₁₄¹³C₃H₁₂Cl₂N₅¹⁵NO₄
SMILES

N#C[13C]1=[15N]N(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)[13C](N[13C]1=O)=O
Synonyms

MGL-3196¹³C₃,¹⁵N; VIA-3196¹³C₃,¹⁵N
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.