Rhodamine B PEG2-NH2
Based on 1 Customer Validation
Rhodamine B PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.32%
- Formula: C32H40ClN3O4
- Molecular Weight:566.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 566.13
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Formula C32H40ClN3O4
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Color Light brown to yellow
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SMILES
O=C(OCCOCCN)C1=CC=CC=C1C2=C(C=CC(N(CC)CC)=C3)C3=[O+]C4=C2C=CC(N(CC)CC)=C4.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 35 mg/mL (61.82 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7664 mL | 8.8319 mL | 17.6638 mL | 44.1595 mL |
| 5 mM | 0.3533 mL | 1.7664 mL | 3.5328 mL | 8.8319 mL | |
| 10 mM | 0.1766 mL | 0.8832 mL | 1.7664 mL | 4.4159 mL | |
| 15 mM | 0.1178 mL | 0.5888 mL | 1.1776 mL | 2.9440 mL | |
| 20 mM | 0.0883 mL | 0.4416 mL | 0.8832 mL | 2.2080 mL | |
| 25 mM | 0.0707 mL | 0.3533 mL | 0.7066 mL | 1.7664 mL | |
| 30 mM | 0.0589 mL | 0.2944 mL | 0.5888 mL | 1.4720 mL | |
| 40 mM | 0.0442 mL | 0.2208 mL | 0.4416 mL | 1.1040 mL | |
| 50 mM | 0.0353 mL | 0.1766 mL | 0.3533 mL | 0.8832 mL | |
| 60 mM | 0.0294 mL | 0.1472 mL | 0.2944 mL | 0.7360 mL |