Ro 18-5364

Cat. No.: HY-115312: Ficha de datos Instrucciones de manejo
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Ro 18-5364 is an inhibitor of gastric H+/K+ ATPase, which has the effect of inhibiting the activity of the enzyme. Ro 18-5364 has a very strong inhibitory effect on gastric mucosal H+/K+ ATPase, and the inhibitory effect is more significant at low pH. At the same time, there is no selectivity difference between the two enantiomers of H+/K+ ATPase, and its inhibitory effect can be studied and verified by a variety of experimental methods, including inhibition of enzyme activity, proton transport, and studies on its binding.

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Ro 18-5364 Estructura química

No. CAS : 101387-98-8

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Descripciòn	Ro 18-5364 is an inhibitor of gastric H+/K+ ATPase, which has the effect of inhibiting the activity of the enzyme. Ro 18-5364 has a very strong inhibitory effect on gastric mucosal H+/K+ ATPase, and the inhibitory effect is more significant at low pH. At the same time, there is no selectivity difference between the two enantiomers of H+/K+ ATPase, and its inhibitory effect can be studied and verified by a variety of experimental methods, including inhibition of enzyme activity, proton transport, and studies on its binding.
Peso molecular	411.52
Fòrmula	C₂₂H₂₅N₃O₃S
No. CAS	101387-98-8
SMILES	O=C1C(C)(C)C2=C(C=C3NC(S(CC4=NC=CC(OC)=C4C)=O)=NC3=C2)C1(C)C
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (266 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Ro 18‐5364, a potent new inhibitor of the gastric (H++ K+)‐ATPase

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ro 18-5364101387-98-8Na+/K+ ATPaseSodium potassium pumpInhibitorinhibitorinhibit

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Ro 18-5364

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Ro 18-5364 Related Classifications

Calculadora de molaridad

Calculadora de dilución