(S)-2-Amino-4,4,4-trifluorobutanoic acid
(S)-2-Amino-4,4,4-trifluorobutanoic acid ((2S)-2-Amino-4,4,4-trifluorobutanoic acid) is a Sestrin-GATOR2 modulator. (S)-2-Amino-4,4,4-trifluorobutanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer.
For research use only. We do not sell to patients.
- CAS No.: 15960-05-1
- Formula: C4H6F3NO2
- Molecular Weight:157.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
(S)-2-Amino-4,4,4-trifluorobutanoic acid (Compound I-4) (25 μM) does not act as a leucine mimetic or antagonist, showing a percentage activity relative to leucine between -40% and 40% in the Sestrin2-GATOR2 binding modulation assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15960-05-1
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Appearance Solid
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Molecular Weight 157.09
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Formula C4H6F3NO2
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Color White to off-white
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SMILES
[C@H](CC(F)(F)F)(C(O)=O)N
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Synonyms
(2S)-2-Amino-4,4,4-trifluorobutanoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)