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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
417 Results for "
Mixture
" in MedChemExpress (MCE) Product Catalog:
Products (417)
417 Results for "Mixture" in MCE Product Catalog:
Cat. No.: HY-B0428D
CAS No.: 130952-46-4
Synonyms: (E/Z)-OKY-046 sodium
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
(E/Z)-Ozagrel sodium [(E/Z)-OKY-046 sodium] is an EZ configuration mixture of Ozagrel sodium (HY-B0428A). Ozagrel sodium (OKY-046 sodium) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel sodium exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel sodium can be used for the study of ischemic stroke, asthma and thromboembolic diseases .
Cat. No.: HY-W011500R
CAS No.: 51805-45-9
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride (Standard)
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Research Areas:
TCEP hydrochloride (Standard) is the analytical standard of TCEP hydrochloride (HY-W011500). This product is intended for research and analytical applications. TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
Cat. No.: HY-W012908
CAS No.: 609-36-9
Target:
DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections .
Cat. No.: HY-L183
531 compounds
Pesticide is a single substance or mixture that can be used to prevent, mitigate, iminate pests or as a plant conditioner, defoliant or desiccant. In recent years, scientists have proposed the concept of "Molecules to Ecosystems", bringing the concept of molecular biology to understand the impact of pesticides, degradation and relationship with the environment or organisms. MCE integrates effective compounds approved as pesticides by agencies such as the Environmental Protection Agency (EPA), China Pesticide Information Network and some insecticidal compounds with potential for agricultural applications.
MCE can provide a library of 531 pesticide compounds that are tool compounds for relevant research.
Cat. No.: HY-182608
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Research Areas:
0.1% Gelatin solution, for cell culture is a biochemical reagent commonly used in cell culture, whose main component is high-molecular-weight polypeptides obtained by hydrolysis of animal collagen. 0.1% Gelatin solution, for cell culture can be used to coat the surfaces of cell culture plates, Petri dishes and other vessels to promote the adhesion and proliferation of mammalian cells .
Cat. No.: HY-182730
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Research Areas:
1% Gelatin solution, for cell culture is a biochemical reagent commonly used in cell culture, whose main component is high-molecular-weight polypeptides obtained by hydrolysis of animal collagen. 1% Gelatin solution, for cell culture can be used to coat the surfaces of cell culture plates, Petri dishes and other vessels to promote the adhesion and proliferation of mammalian cells .
Cat. No.: HY-101399SA
Synonyms: H-γ-Glu-Phe-OH-13C9,15N TFA; γ-Glutamylphenylalanine-13C9,15N TFA
Cat. No.: HY-118590A
CAS No.: 21416-68-2
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is a DNA Topoisomerase II inhibitor. ICRF-193 can inhibit DNA syntheses and induces apoptosis. ICRF-193 exhibits anti-cancer and anti-inflammation effects. ICRF-193 shows cardioprotective effect against anthracycline toxicity to cardiomyocytes. ICRF-193 can be used for the researches of cancer, infection, inflammation and cardiovascular disease, such as acute promyelocytic leukemia .
Cat. No.: HY-167680
CAS No.: 483369-58-0
Synonyms: GSK823093
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Research Areas:
Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
Cat. No.: HY-173630A
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Research Areas:
(R)-BMS-986449 is the racemic mixture of BMS-986449 (HY-173630). BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors .
Cat. No.: HY-N13772
CAS No.: 55812-91-4
Synonyms: (+)-Dihydroisorhamnetin
Target:
Cat. No.: HY-W133898
CAS No.: 73049-73-7
Cat. No.: HY-W700621
CAS No.: 1189959-10-1
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride-d12
Cat. No.: HY-W747104
CAS No.: 52957-16-1
Category:
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Cat. No.: HY-D3362
Research Areas:
RL420 is an RNA-selective fluorescent covalent probe that binds covalently to the 2′-hydroxyl group of RNA via an acylimidazole-mediated reaction. RL420 has excitation/emission wavelengths of 420/452 nm, exhibits a 150-fold selectivity for RNA over DNA, and shows high labeling efficiency. RL420 can be used in studies related to in vitro RNA labeling, gel imaging, and blue fluorescent imaging of RNA in fixed cells (e.g., nucleoli) .
Synonyms: (±)-BAY-1251152; (±)-VIP152
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Research Areas:
(±)-Enitociclib ((±)-BAY-1251152) is the racemic mixture of Enitociclib (HY-103019E). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC + lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
Target:
Cat. No.: HY-126404
CAS No.: 65072-00-6
Research Areas:
Casein hydrolysate is an orally effective, multi-functional mixture of bioactive peptides, a hydrolysis product of casein (HY-125865), containing ACE inhibitors and immunomodulatory target regulators, among others. Casein hydrolysate releases short-chain bioactive peptides through enzymatic hydrolysis of casein, increasing cellular glutathione and catalase levels, enhancing ConA-induced IL-2 production, and exhibiting metal ion chelation, free radical scavenging, antibacterial, and mineral absorption-promoting effects. Casein hydrolysate lowers blood pressure by inhibiting angiotensin-converting enzyme (ACE) and reducing bradykinin degradation .
Cat. No.: HY-129836R
CAS No.: 26889-93-0
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L-Amoxicillin (Standard) is the analytical standard of L-Amoxicillin. This product is intended for research and analytical applications. L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application .
Cat. No.: HY-162596A
CAS No.: 863638-93-1
Synonyms: (Rac)-BA-1049
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Research Areas:
(Rac)-NRL-1049 is the racemic mixture of NRL-1049 (BA-1049 (free base)) (HY-162596). NRL-1049 is an orally available and selective ROCK2 inhibitor with IC50 values of 0.59 µM for ROCK2 and 26 µM for ROCK1, respectively. NRL-1049 modulates ROCK signaling, preserves blood-brain barrier integrity, reduces edema, seizures and hemorrhage, and alleviates cerebral cavernous malformation lesion burden. NRL-1049 can be used for the study of acute brain injury, ischemic stroke, and cerebral cavernous malformations .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
