3'-O-Methyltaxifolin
3'-O-Methyltaxifolin ((+)-Dihydroisorhamnetin) is a dihydroflavanol found in Pulicaria jaubertii. A mixture of these alcohol compounds including 3'-O-Methyltaxifolin found in Pulicaria jaubertii exhibits antitumor activity with IC50 values of 19.1 μg, 20.0 μg, and 24.1 μg against prostate cancer (PC-3), breast cancer (MCF-7), and hepatocellular carcinoma (HepG-2) cell lines, respectively. Furthermore, 3'-O-Methyltaxifolin can induce cell apoptosis, making it a promising candidate for anticancer research..
For research use only. We do not sell to patients.
- CAS No.: 55812-91-4
- Formula: C16H14O7
- Molecular Weight:318.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 55812-91-4
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Molecular Weight 318.28
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Formula C16H14O7
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SMILES
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(OC)=C(C=C3)O)[C@H]1O
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Synonyms
(+)-Dihydroisorhamnetin
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ragab EA, et al. A new monoterpene glucoside and complete assignments of dihydroflavonols of Pulicaria jaubertii: potential cytotoxic and blood pressure lowering activity. Nat Prod Res. 2016 Jun;30(11):1280-8. [Content Brief]
[2]. Mohammed HA, et al. Comparative Anticancer Potentials of Taxifolin and Quercetin Methylated Derivatives against HCT-116 Cell Lines: Effects of O-Methylation on Taxifolin and Quercetin as Preliminary Natural Leads. ACS Omega. 2022 Dec 7;7(50):46629-46639. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)