3'-O-Methyltaxifolin
3'-O-Methyltaxifolin ((+)-Dihydroisorhamnetin) is a dihydroflavanol found in Pulicaria jaubertii. A mixture of these alcohol compounds including 3'-O-Methyltaxifolin found in Pulicaria jaubertii exhibits antitumor activity with IC50 values of 19.1 μg, 20.0 μg, and 24.1 μg against prostate cancer (PC-3), breast cancer (MCF-7), and hepatocellular carcinoma (HepG-2) cell lines, respectively. Furthermore, 3'-O-Methyltaxifolin can induce cell apoptosis, making it a promising candidate for anticancer research..
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 55812-91-4
- Formel: C16H14O7
- Molecular Weight:318.28
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
-
CAS. Nr. 55812-91-4
-
Molecular Weight 318.28
-
Formel C16H14O7
-
SMILES
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(OC)=C(C=C3)O)[C@H]1O
-
Synonyms
(+)-Dihydroisorhamnetin
-
Structure Classification
-
Initial Source
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Ragab EA, et al. A new monoterpene glucoside and complete assignments of dihydroflavonols of Pulicaria jaubertii: potential cytotoxic and blood pressure lowering activity. Nat Prod Res. 2016 Jun;30(11):1280-8. [Content Brief]
[2]. Mohammed HA, et al. Comparative Anticancer Potentials of Taxifolin and Quercetin Methylated Derivatives against HCT-116 Cell Lines: Effects of O-Methylation on Taxifolin and Quercetin as Preliminary Natural Leads. ACS Omega. 2022 Dec 7;7(50):46629-46639. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)