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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
GLYT2
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "GLYT2" in MCE Product Catalog:
Synonyms: NA-Gly-d8
Cat. No.: HY-113202S1
CAS No.: 2936622-19-2
Cat. No.: HY-186238
CAS No.: 1440797-80-7
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VVZ-068 is a benzamide derivative and also a GlyT2/5HT2A antagonist. VVZ-068 alleviates neuropathic mechanical hyperalgesia in a rat model of mechanical allodynia. VVZ-068 is applicable for pain-related research .
Cat. No.: HY-RS13314
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SLC6A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC6A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13316
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Slc6a5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc6a5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-148708A
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Oleoyl-D-lysine sodium is a selective Glycine Transporter-2 (GlyT2) inhibitor based on lipid. Oleoyl-D-lysine sodium reverses neuropathic pain in mice, shows antidrowsiness effect on chronic neuropathic pain. Oleoyl-D-lysine sodium is safe and effective without respiratory depression .
Cat. No.: HY-RS13315
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Slc6a5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc6a5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05407
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GGTA1 Human Pre-designed siRNA Set A contains three designed siRNAs for GGTA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-107527R
CAS No.: 495076-64-7
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Org 25543 hydrochloride (Standard) is the analytical standard of Org 25543 (hydrochloride) (HY-107527). This product is intended for research and analytical applications. Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor (IC50: 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice [2] .
Cat. No.: HY-109067AR
CAS No.: 1440796-75-7
Synonyms: VVZ-149 hydrochloride (Standard)
Research Areas:
Opiranserin hydrochloride (Standard) is the analytical standard of Opiranserin (hydrochloride) (HY-109067A). This product is intended for research and analytical applications. Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
